Analysis of the numbers and structure of blood cells is important in the diagnosis and monitoring of disease and infection. These tests can help us identify a problem before clinical signs, or symptoms, appear. But what exactly are we looking for when we do a blood draw?
There are 3 common tests carried out using red blood cells: packed cell volume, hemoglobin concentration, and red blood cell count. All 3 are interrelated and help us diagnose diseases. When the proportion of red blood cells is high, the condition is called polycythemia. Polycythemia is common when a pet has dehydration or diarrhea. A low packed cell volume may suggest anemia or bleeding. The results of the tests on red blood cells can tell us a lot about the way your pet’s body is functioning and suggest possible health problems.
There are 5 main types of white blood cells. Neutrophils are the most common type of white blood cell. They engulf (“eat”) infectious particles such as bacteria. They increase in number during inflammation, infection, and short-term stress. A related type of white blood cell is the eosinophil. The number of eosinophils goes up during allergic reactions and some tissue injuries. Their number also goes up in response to certain tumors and parasites. Basophils are the least common type of white blood cell. They are also related to neutrophils and eosinophils. An increase in the number of basophils is associated with inflammation. Monocytes are large cells that serve mainly as phagocytes and increase in number during chronic diseases. Lymphocytes are the white blood cells responsible for antibody production and cell-mediated immune responses. Large increases in the number of lymphocytes often indicates leukemia, a type of cancer.
Platelets are cell-like particles in the blood. Another name for platelets is thrombocytes. Platelets are much smaller than red or white blood cells. They perform a critical role in the clotting process to repair damaged blood vessels. Thus, injuries often prompt a large increase in number of platelets. Some autoimmune diseases, blood clotting disorders, and bone marrow problems cause a decrease in the number of platelets.
Having these tests performed can help point to a diagnosis, particularly if the animal has signs and a history that could make it difficult to determine the problem. Below is a basic group of blood tests for pets and based on the results of this group of tests, other tests may be carried out as needed to reach a definite diagnosis.
Total Protein: Increases due to dehydration or inflammation; may decrease due to bleeding, malnutrition, or congestive heart failure
Albumin: Increases due to dehydration; may decrease due to bleeding, congestive heart failure, or liver failure
Globulin: Calculated as the difference between total protein and albumin
Urea: Increases due to certain dietary excesses or deficiencies, congestive heart failure, kidney failure, or a ruptured bladder; decreases may be due to liver failure or low levels of dietary protein
Creatinine: Increases may be due to kidney disorders, muscle damage, or a ruptured bladder
Glucose: Increases may be caused by diabetes or short-term stress; decreases may be found in cases of neurologic disease or malnutrition
ALT and ALP: Increases in these enzymes may indicate liver damage, muscle damage, or increased thyroid gland activity
Whether your pet is a senior, or still young in years, routine bloodwork is an important part of your pet’s healthcare.)
We want to make it even easier to help keep your pet healthy, so we are offering 20% off Bloodwork in the month of September when your pet has a Wellness Exam!